Destructive fat tissue engineering using photodynamic and selective photothermal effects

Valery V. Tuchin; Irina Yu. Yanina; Georgy V. Simonenko

doi:10.1117/12.812164

24 February 2009 Destructive fat tissue engineering using photodynamic and selective photothermal effects

Valery V. Tuchin, Irina Yu. Yanina, Georgy V. Simonenko

Proceedings Volume 7179, Optics in Tissue Engineering and Regenerative Medicine III; 71790C (2009) https://doi.org/10.1117/12.812164
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Destructive fat tissue engineering could be realized using the optical method, which provides reduction of regional or site-specific accumulations of subcutaneous adipose tissue on the cell level. We hypothesize that light irradiation due to photodynamic and selective photothermal effects may lead to fat cell lypolytic activity (the enhancement of lipolysis of cell triglycerides due to expression of lipase activity and cell release of free fat acids (FFAs) due to temporal cell membrane porosity), and cell delayed killing due to apoptosis caused by the induced fat cell stress and/or limited cell necrosis.

Citation Download Citation

Valery V. Tuchin, Irina Yu. Yanina, and Georgy V. Simonenko "Destructive fat tissue engineering using photodynamic and selective photothermal effects", Proc. SPIE 7179, Optics in Tissue Engineering and Regenerative Medicine III, 71790C (24 February 2009); https://doi.org/10.1117/12.812164

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