Imaging of highly scattering media by spatially modulated pulsed light

A. Bassi; C. D'Andrea; G. Valentini; R. Cubeddu; S. Arridge

doi:10.1117/12.809608

23 February 2009 Imaging of highly scattering media by spatially modulated pulsed light

A. Bassi, C. D'Andrea, G. Valentini, R. Cubeddu, S. Arridge

Proceedings Volume 7174, Optical Tomography and Spectroscopy of Tissue VIII; 71740E (2009) https://doi.org/10.1117/12.809608
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

The use of spatially modulated light is finding application in biomedical optics having potential use in imaging and tomography of tissues and small animals. We describe the time-resolved propagation of spatial frequencies in turbid media. We present a set-up based on a ps laser source, spatially modulated by a micro-mirror device and a time-gated intensifier. We discuss the relevant information content that can be useful for imaging of tissues, in terms of the spatial Fourier components of the propagating pulse. We demonstrate that high spatial frequencies appear in the early time-gated signal whereas low frequencies persist for longer times and that the combined use of high spatial frequencies and early time gates can be used to improve the resolution in imaging.

Citation Download Citation

A. Bassi, C. D'Andrea, G. Valentini, R. Cubeddu, and S. Arridge "Imaging of highly scattering media by spatially modulated pulsed light", Proc. SPIE 7174, Optical Tomography and Spectroscopy of Tissue VIII, 71740E (23 February 2009); https://doi.org/10.1117/12.809608

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KEYWORDS

Spatial frequencies

Modulation

Picosecond phenomena

Spatial resolution

Image resolution

Tissues

Linear filtering

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