Maximum likelihood estimation of depth reflectance in time-domain optical coherence tomography

Sherif Sherif; Costel Flueraru; Youxin Mao; Shoude Chang

doi:10.1117/12.728024

11 July 2007 Maximum likelihood estimation of depth reflectance in time-domain optical coherence tomography

Sherif Sherif, Costel Flueraru, Youxin Mao, Shoude Chang

Proceedings Volume 6627, Optical Coherence Tomography and Coherence Techniques III; 66270S (2007) https://doi.org/10.1117/12.728024
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

We use a random process model for the photocurrent in time-domain optical coherence tomography (TD-OCT) to obtain a maximum likelihood estimate of the reflectance at different depths of an object. This statistical image restoration approach is generally more effective than the previously reported deterministic methods, as it accounts for the statistics of the noise. We also present an expression for the Fisher information matrix in TD-OCT, which could be used to optimize TD-OCT setups. We present theoretical results which we apply to a simulated TD-OCT imaging example.

Citation Download Citation

Sherif Sherif, Costel Flueraru, Youxin Mao, and Shoude Chang "Maximum likelihood estimation of depth reflectance in time-domain optical coherence tomography", Proc. SPIE 6627, Optical Coherence Tomography and Coherence Techniques III, 66270S (11 July 2007); https://doi.org/10.1117/12.728024

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