Determination of optical properties in turbid medium based on time-resolved determination

Dongli Qin; Zheng Ma; Feng Gao; Huijuan Zhao

doi:10.1117/12.741361

1 May 2007 Determination of optical properties in turbid medium based on time-resolved determination

Dongli Qin, Zheng Ma, Feng Gao, Huijuan Zhao

Proceedings Volume 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine; 65340T (2007) https://doi.org/10.1117/12.741361
Event: Fifth International Conference on Photonics and Imaging in Biology and Medicine, 2006, Wuhan, China

Abstract

In this article, we briefly described a time-correlated single photon counting (TCSPC) system specifically designed for extracting the optical properties in turbid medium. This system was evaluated by use of two sets of liquid tissue-simulating phantoms containing different concentrations of Intralipid-10% as scatters and India ink as absorbers. With the distribution of times of flight (DTOF) of photons measured by the TCSPC system, some featured parameters, such as the mean time of flight and the variance of DTOF were calculated. Based on these parameters, we developed a simple and fast method to obtain the absorption coefficient μ_a and reduced scattering coefficient μ_s of the turbid medium. Furthermore, the accuracy of the method was validated using the Monte Carlo simulations. It was found that the optical properties could be extracted with this method, which was much faster than the conventional curve-fitting procedure. Our method could be useful in on-line monitoring of optical properties of biological tissue.

Citation Download Citation

Dongli Qin, Zheng Ma, Feng Gao, and Huijuan Zhao "Determination of optical properties in turbid medium based on time-resolved determination", Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 65340T (1 May 2007); https://doi.org/10.1117/12.741361

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available