Design of an image sensor for an ultra-high-speed and ultra-high-sensitive video microscope

Nao Otsuka; Vo Le Cuong; Pavel Karimov; Kohsei Takehara; T. Goji Etoh

doi:10.1117/12.706072

29 January 2007 Design of an image sensor for an ultra-high-speed and ultra-high-sensitive video microscope

Nao Otsuka, Vo Le Cuong, Pavel Karimov, Kohsei Takehara, T. Goji Etoh

Proceedings Volume 6491, Videometrics IX; 649111 (2007) https://doi.org/10.1117/12.706072
Event: Electronic Imaging 2007, 2007, San Jose, CA, United States

Abstract

This paper outlines a special microscope under development, named "Ultra-high-speed bionanoscope" for ultra-highspeed imaging in biological applications, and preliminary design of the image sensor, which is the key component in the system. The ultra-high-speed bionanoscope consists of two major subsystems: a video camera operating at more than 10 Mfps with ultra-high-sensitivity and the special microscope to minimize loss of light for seriously reduced illumination light energy due to the ultra-high-speed imaging. The ultra-high-frame rate is achieved by introducing a special structure of a CCD imager, the ISIS, In-situ Storage Image Sensor, invented by Etoh and Mutoh. The ISIS has an array of pixels each of which equips with a slanted linear CCD storage area for more than 100 image signals for reproduction of smoothly moving images. The ultra-high-sensitivity of the sensor of less than 10 photons is achieved by introducing three existing technologies, backside-illumination, cooling, and the CCM, Charge Carrier Multiplication invented by Hynecek.

Citation Download Citation

Nao Otsuka, Vo Le Cuong, Pavel Karimov, Kohsei Takehara, and T. Goji Etoh "Design of an image sensor for an ultra-high-speed and ultra-high-sensitive video microscope", Proc. SPIE 6491, Videometrics IX, 649111 (29 January 2007); https://doi.org/10.1117/12.706072

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