Enhancement of fluorescence signal with one dimensional photonic band gap structure

Qiwen Zhan

doi:10.1117/12.697580

10 February 2007 Enhancement of fluorescence signal with one dimensional photonic band gap structure

Qiwen Zhan

Proceedings Volume 6444, Ultrasensitive and Single-Molecule Detection Technologies II; 644408 (2007) https://doi.org/10.1117/12.697580
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

In this paper, we propose to use one dimensional (1D) photonic band gap (PBG) structure to enhance the florescence excitation and collection for single molecule level imaging and sensing applications. In the setup, the incidence of excitation and the collection of the florescence are located on separate sides of the 1D PBG structure. The 1D PBG structure creates total internal reflection for the excitation wavelength. With carefully chosen 1D PBG structures, an enhanced evanescent field for the excitation wavelength at the interface between the last layer of the PBG and sample can be obtained. Meanwhile, the 1D PBG structure is designed such that it also serves as an omnidirectional reflector for the florescence signal, leading to higher collection efficiency. The combination of stronger excitation field and improved detection efficiency gives rise to two orders of magnitude enhancement of florescence signal.

Citation Download Citation

Qiwen Zhan "Enhancement of fluorescence signal with one dimensional photonic band gap structure", Proc. SPIE 6444, Ultrasensitive and Single-Molecule Detection Technologies II, 644408 (10 February 2007); https://doi.org/10.1117/12.697580

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