Paper
23 February 2006 Multiphoton nanosurgery in cells and tissues
Iris Riemann, Frank Stracke, Daniel Sauer, Sven Martin, Karsten König
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Abstract
Near infrared (NIR) femtosecond laser microscopes enable the user to perform highly precise nanosurgery. Tissue components, cells and single organelles of cells inside tumor-sphaeroids and tissues can be precisely manipulated and optically knocked out without collateral damage. In addition, the monitoring effects of nanosurgery in situ using two photon excitation of auto fluorescence of endogenous fluorophores can be performed quite easily with a sub-cellular resolution. This method may become a useful instrument for nano manipulation and nano-surgery in several fields of life sciences.
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Iris Riemann, Frank Stracke, Daniel Sauer, Sven Martin, and Karsten König "Multiphoton nanosurgery in cells and tissues", Proc. SPIE 6089, Multiphoton Microscopy in the Biomedical Sciences VI, 608918 (23 February 2006); https://doi.org/10.1117/12.646096
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KEYWORDS
Tissues

Near infrared

Femtosecond phenomena

Luminescence

Microscopes

Biopsy

Laser scanners

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