Paper
1 September 2005 Cost-efficient THz-resonators for label-free detection of DNA hybridization
M. Nagel, H. Kurz
Author Affiliations +
Abstract
THz-technology provides new ground for label-free detection of biomolecules by taking advantage of existing hybridization techniques. Recent developments for label-free analysis of genetic material with femtomol-sensitivity using integrated functionalized THz sensors are presented. In comparison to former planar strip line approaches, the modular concept based on parallel-plate waveguides presented here provides a cost-efficient solution given the exchangeability, disposability or reusability of components. Three different fabrication technologies for disposable THz resonator chips are investigated.
© (2005) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
M. Nagel and H. Kurz "Cost-efficient THz-resonators for label-free detection of DNA hybridization", Proc. SPIE 5864, Novel Optical Instrumentation for Biomedical Applications II, 58640M (1 September 2005); https://doi.org/10.1117/12.632935
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KEYWORDS
Resonators

Waveguides

Terahertz radiation

Sensors

Silicon

Micromachining

Signal attenuation

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