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13 July 2004 End-to-end small bowel anastomosis by temperature controlled CO2 laser soldering and an albumin stent: a feasibility study
David Simhon M.D., Doron Kopelman M.D., Moshe Hashmonai M.D., Irena Vasserman, Michael Dror, Tamar Vasilyev, Marissa Halpern M.D., Naam Kariv, Abraham Katzir
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Proceedings Volume 5312, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIV; (2004) https://doi.org/10.1117/12.528954
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States
Abstract
Introduction: A feasibility study of small intestinal end to end anastomosis was performed in a rabbit model using temperature controlled CO2 laser system and an albumin stent. Compared with standard suturing or clipping, this method does not introduce foreign materials to the repaired wound and therefore, may lead to better and faster wound healing of the anastomotic site. Methods: Transected rabbits small intestines were either laser soldered using 47% bovine serum albumin and intraluminal albumin stent or served as controls in which conventional continuous two-layer end to end anastomosis was performed manually. The integrity of the anastomosis was investigated at the 14th postoperative day. Results: Postoperative course in both treatments was uneventful. The sutured group presented signs of partial bowel obstruction. Macroscopically, no signs of intraluminal fluid leakage were observed in both treatments. Yet, laser soldered intestinal anastomoses demonstrated significant superiority with respect to adhesions and narrowing of the intestinal lumen. Serial histological examinations revealed better wound healing characteristics of the laser soldered anastomotic site. Conclusion: Laser soldering of intestinal end to end anastomosis provide a faster surgical procedure, compared to standard suture technique, with better wound healing results. It is expected that this technique may be adopted in the future for minimal invasive surgeries.
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David Simhon M.D., Doron Kopelman M.D., Moshe Hashmonai M.D., Irena Vasserman, Michael Dror, Tamar Vasilyev, Marissa Halpern M.D., Naam Kariv, and Abraham Katzir "End-to-end small bowel anastomosis by temperature controlled CO2 laser soldering and an albumin stent: a feasibility study", Proc. SPIE 5312, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIV, (13 July 2004); https://doi.org/10.1117/12.528954
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KEYWORDS
Laser welding
Gas lasers
Wound healing
Carbon monoxide
Control systems
Laser systems engineering
Laser tissue interaction
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