Multiphoton imaging in the detection of malignancy in the oesophagus

Catherine A. Kendall; Karen McCloskey; Nicholas Stone; Hugh Barr; Douglas Greenhalgh

doi:10.1117/12.500486

9 October 2003 Multiphoton imaging in the detection of malignancy in the oesophagus

Catherine A. Kendall, Karen McCloskey, Nicholas Stone, Hugh Barr, Douglas Greenhalgh

Proceedings Volume 5139, Confocal, Multiphoton, and Nonlinear Microscopic Imaging; (2003) https://doi.org/10.1117/12.500486
Event: European Conferences on Biomedical Optics 2003, 2003, Munich, Germany

Abstract

A preliminary investigation of tissue autofluorescence and uptake of the photosensitiser protoporphyrin IX (PpIX) has been investigated using multiphoton imaging of excised oesophageal tissue. The technique has indicated that changes in collagen structure may be a potential marker for high-grade dysplasia and adenocarcinoma. Changes in the localisation of PpIX with the development of malignancy in oesophageal tissue were also visualised.

Citation Download Citation

Catherine A. Kendall, Karen McCloskey, Nicholas Stone, Hugh Barr, and Douglas Greenhalgh "Multiphoton imaging in the detection of malignancy in the oesophagus", Proc. SPIE 5139, Confocal, Multiphoton, and Nonlinear Microscopic Imaging, (9 October 2003); https://doi.org/10.1117/12.500486

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