Novel x-ray source for dual-energy subtraction angiography

Alessandra Tuffanelli; Angelo Taibi; G. Baldazzi; Dante Bollini; Mirco Gombia; L. Ramello; Mauro Gambaccini

doi:10.1117/12.465572

3 May 2002 Novel x-ray source for dual-energy subtraction angiography

Alessandra Tuffanelli, Angelo Taibi, G. Baldazzi, Dante Bollini, Mirco Gombia, L. Ramello, Mauro Gambaccini

Proceedings Volume 4682, Medical Imaging 2002: Physics of Medical Imaging; (2002) https://doi.org/10.1117/12.465572
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

In angiography practice an iodate contrast medium is injected in patient vessels with catheters. The absorption of x-rays raises immediately after the iodine K-edge energy. In digital subtraction angiography, two images are used, acquired before and after the injection of the contrast medium, respectively. The vessels morphology result from the difference of images so obtained. This technique involves a non-negligible risk of morbidity or mortality, due to high concentration of injected contrast agent. We are investigating a new source which produces two thin parallel quasi-monochromatic beams - having peak energies centered before and after the iodine K-edge energy, respectively - by using a conventional x-ray tube and a highly oriented pyrolytic graphite mosaic crystal. The polychromatic x-rays incident on the crystal are monochromatized by Bragg diffraction and split in two thin parallel beams, by means of a collimating system. These two beams impinge on the phantom simulating patient vessels and are detected with solid-state array detectors. The image results as difference between the remaining intensities of two beams. We report a preliminary study of the new technique performed both with theoretical stimulations and experimental measurements. Results of computer simulation give information about characteristics as size and quality of the quasi- monochromatic beams, that should be considered in detail to design a system dedicated to the clinical practice. Experimental measurements have been performed on a small- field detector in order to shows the enhancement of image contrast obtained with the application of the new technique.

Citation Download Citation

Alessandra Tuffanelli, Angelo Taibi, G. Baldazzi, Dante Bollini, Mirco Gombia, L. Ramello, and Mauro Gambaccini "Novel x-ray source for dual-energy subtraction angiography", Proc. SPIE 4682, Medical Imaging 2002: Physics of Medical Imaging, (3 May 2002); https://doi.org/10.1117/12.465572

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available