Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm

Nelson Salas Jr.; Fabrice Manns; Jean-Marie A. Parel; Peter J. Milne; Manuel Figueroa; David B. Denham; David S. Robinson M.D.

doi:10.1117/12.438871

17 June 2002 Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm

Nelson Salas Jr., Fabrice Manns, Jean-Marie A. Parel, Peter J. Milne, Manuel Figueroa, David B. Denham, David S. Robinson M.D.

Author Affiliations +

Proceedings Volume 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII; (2002) https://doi.org/10.1117/12.438871
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

Purpose: the purpose of these experiments was to evaluate the temperature and predicted cell kill distribution during LITT of breast tissue phantoms at 940nm and compare with the results of previous experiments ar 830 nm and 980 nm. Material and Methods: A Dornier Medilas D Skinpulse 940 nm diode lase system coupled to a Dornier D-6111-T2 fiber (Dornier Surgical Products, Phoenix, AZ) was used to irradiate the porcine tissue three times at approximately 5 W for 10 minutes. Results: The initial rate of temperature increase at 940 nm for locations 5, 10, and 15 mm from the fiber axis ranged from 0.076 to 0.142 °C/s, 0.027 to 0.041 °C/s, and 0.008 to 0.013 °C/s, respectively, wile the maximum temperature increase ranged from 37.8 to 46.9 °C, 19.3 to 26.1 °C, 8.6 to 13.0 °C, respectively, temperature curves hed lower slopes at 940 nm than at 830 nm and 980 nm. the maximum temperature increase was higher at 940 nm than at 830 nm. Predicted area of 100% cell kill was approximately 2 cm by 2 cm Conclusion: Results of experiments at 940 nm were more comparable to those at 980 nm than at 830 nm.

Citation Download Citation

Nelson Salas Jr., Fabrice Manns, Jean-Marie A. Parel, Peter J. Milne, Manuel Figueroa, David B. Denham, and David S. Robinson M.D. "Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm", Proc. SPIE 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, (17 June 2002); https://doi.org/10.1117/12.438871

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available