Optical pathlength meter for near-infrared spectroscopy

Iain D. C. Tullis; David T. Delpy

doi:10.1117/12.447138

31 October 2001 Optical pathlength meter for near-infrared spectroscopy

Iain D. C. Tullis, David T. Delpy

Proceedings Volume 4432, Diagnostic Optical Spectroscopy in Biomedicine; (2001) https://doi.org/10.1117/12.447138
Event: European Conferences on Biomedical Optics, 2001, Munich, Germany

Abstract

Many commercial clinical Near Infrared Spectroscopy (NIRS) instruments rely upon estimates of the optical pathlength of tissue based upon the optode spacing multiplied by an average differential pathlength factor(DPF) for the tissue under investigation. Significant variation in the published DPF is the major source of error in the NIRS data quantification. To reduce this error, an inexpensive, stand-alone, single wavelength, single frequency optical pathlength meter based on the homodyne phase method was constructed for clinical use with an existing NIRO 300 instrument (Hamamatsu Photonics KK). The construction and testing of the optical pathlength meter is discussed.

Citation Download Citation

Iain D. C. Tullis and David T. Delpy "Optical pathlength meter for near-infrared spectroscopy", Proc. SPIE 4432, Diagnostic Optical Spectroscopy in Biomedicine, (31 October 2001); https://doi.org/10.1117/12.447138

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