Analysis of evolving processes in pulmonary nodules using a sequence of three-dimensional thoracic images

Yoshiki Kawata; Noboru Niki; Hironobu Omatsu; Masahiko Kusumoto; Ryutaro Kakinuma; Kiyoshi Mori; Hiroyuki Nishiyama; Kenji Eguchi; Masahiro Kaneko; Noriyuki Moriyama

doi:10.1117/12.431081

3 July 2001 Analysis of evolving processes in pulmonary nodules using a sequence of three-dimensional thoracic images

Yoshiki Kawata, Noboru Niki, Hironobu Omatsu, Masahiko Kusumoto, Ryutaro Kakinuma, Kiyoshi Mori, Hiroyuki Nishiyama, Kenji Eguchi, Masahiro Kaneko, Noriyuki Moriyama

Author Affiliations +

Proceedings Volume 4322, Medical Imaging 2001: Image Processing; (2001) https://doi.org/10.1117/12.431081
Event: Medical Imaging 2001, 2001, San Diego, CA, United States

Abstract

This paper presents a method to analyze volume evolutions of pulmonary nodules for discrimination between malignant and benign nodules. Our method consists of four steps; The 3D rigid registration of the two successive 3D thoracic CT images, the 3D affine registration of the two successive region-of-interest (ROI) images, non rigid registration between local volumetric ROIs, and analysis of the local displacement field between successive temporal images. In preliminary study, the method was applied to the successive 3D thoracic images of two pulmonary lesions including a metastasis malignant case and an inflammatory benign to quantify the evolving process in the pulmonary nodules and surrounding structure. The time intervals between successive 3D thoracic images for the benign and malignant cases were 120 and 30 days, respectively. From the display of the displacement fields and the contrasted image by the vector field operator based on the Jacobian, it was observed that the benign case reduced in the volume and the surrounding structure was involved into the nodule in the evolution process. It was also observed that the malignant case expanded in the volume. These experimental results indicate that our method is a promising tool to quantify how the lesions evolve their volume and surrounding structures.

Citation Download Citation

Yoshiki Kawata, Noboru Niki, Hironobu Omatsu, Masahiko Kusumoto, Ryutaro Kakinuma, Kiyoshi Mori, Hiroyuki Nishiyama, Kenji Eguchi, Masahiro Kaneko, and Noriyuki Moriyama "Analysis of evolving processes in pulmonary nodules using a sequence of three-dimensional thoracic images", Proc. SPIE 4322, Medical Imaging 2001: Image Processing, (3 July 2001); https://doi.org/10.1117/12.431081

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available