Automated microscopy system for peripheral blood cells

Sergei F. Boev; Vladimir V. Sazonov; Gennady I. Kozinets; Valery M. Pogorelov; Alexander A. Gusev; Farida V. Korobova; Alexander G. Vinogradov; Natalya V. Verdenskaya; Irina A. Ivanova

doi:10.1117/12.407651

22 November 2000 Automated microscopy system for peripheral blood cells

Sergei F. Boev, Vladimir V. Sazonov, Gennady I. Kozinets, Valery M. Pogorelov, Alexander A. Gusev, Farida V. Korobova, Alexander G. Vinogradov, Natalya V. Verdenskaya, Irina A. Ivanova

Author Affiliations +

Proceedings Volume 4163, Optical Techniques and Instrumentation for the Measurement of Blood Composition, Structure, and Dynamics; (2000) https://doi.org/10.1117/12.407651
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

The report describes the instrument ASPBS (Automated Screening of Peripheral Blood Cells) designed for an automated analysis of dry blood smears. The instrument is based on computer microscopy and uses dry blood smears prepared according to the standard Romanovskii-Giemza procedure. In comparison with the well-known flow cytometry systems, our instrument provides more detailed information and offers an opporunity of visualizing final results. The basic performances of the instrument are given. Software of this instrument is based on digital image processing and image recognition procedures. It is pointed out that the instrument can be used as a fairly universal tool in scientific research, public demonstrations, in medical treatment, and in medical education. The principle used as the basis of the instrument appeared adequate for creating an instrument version serviceable even during space flights where standard manual procedures and flow cytometry systems fail. The benefit of the use of the instrument in clinical laboratories is described.

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Sergei F. Boev, Vladimir V. Sazonov, Gennady I. Kozinets, Valery M. Pogorelov, Alexander A. Gusev, Farida V. Korobova, Alexander G. Vinogradov, Natalya V. Verdenskaya, and Irina A. Ivanova "Automated microscopy system for peripheral blood cells", Proc. SPIE 4163, Optical Techniques and Instrumentation for the Measurement of Blood Composition, Structure, and Dynamics, (22 November 2000); https://doi.org/10.1117/12.407651

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KEYWORDS

Blood

Statistical analysis

Microscopes

Image segmentation

Microscopy

Databases

Visualization

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