Laser skin resurfacing using a frequency-doubled Nd:YAG laser after topical application of an exogenous chromophore

Chryslain C. Sumian; Franck Pitre; Beatrice Gauthier; Martine Bouclier; Serge R. Mordon

doi:10.1117/12.339153

4 February 1999 Laser skin resurfacing using a frequency-doubled Nd:YAG laser after topical application of an exogenous chromophore

Chryslain C. Sumian, Franck Pitre, Beatrice Gauthier, Martine Bouclier, Serge R. Mordon

Author Affiliations +

Proceedings Volume 3564, Medical Applications of Lasers in Dermatology, Cardiology, Ophthalmology, and Dentistry II; (1999) https://doi.org/10.1117/12.339153
Event: BiOS Europe '98, 1998, Stockholm, Sweden

Abstract

Laser skin resurfacing is usually performed with CO₂ or Er:YAG lasers. Since frequency doubled Nd:YAG laser (532 nm) is already used in dermatology for angiodysplasias treatment, a new laser resurfacing method was investigated. In this study, we evaluated the possibility to achieve skin resurfacing using a 532 nm laser after topical application of an exogenous chromophore. This exogenous chromophore consisted in carbon dispersed and mixed with film-forming polymers and water. The resultant solution was applied to the skin surface using an air brush. Validation was performed in vivo on rat skin using the following laser parameters (532 nm, 2.7 W, 1 mm, 50 - 200 ms). Skin biopsies were taken to evaluate histological changes and to quantify epidermis ablation and dermis coagulation. Wound healing was followed up. The results showed that dermis coagulation depth increased as a function of exposure time. In conclusion, the concept of applying a carbon-based solution onto skin in order to obtain firstly laser light conversion into heat and secondly an heat transfer to the tissue is valid for laser skin resurfacing. By selecting exposure time, dermis coagulation depth can be either the one observed with Er:YAG laser or the one obtained with CO₂ laser.

Citation Download Citation

Chryslain C. Sumian, Franck Pitre, Beatrice Gauthier, Martine Bouclier, and Serge R. Mordon "Laser skin resurfacing using a frequency-doubled Nd:YAG laser after topical application of an exogenous chromophore", Proc. SPIE 3564, Medical Applications of Lasers in Dermatology, Cardiology, Ophthalmology, and Dentistry II, (4 February 1999); https://doi.org/10.1117/12.339153

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