Application of a novel laser Doppler tester including a sustainable tissue phantom

Wiendelt Steenbergen; Frits F. M. de Mul

doi:10.1117/12.311891

19 June 1998 Application of a novel laser Doppler tester including a sustainable tissue phantom

Wiendelt Steenbergen, Frits F. M. de Mul

Proceedings Volume 3252, Optical Diagnostics of Biological Fluids III; (1998) https://doi.org/10.1117/12.311891
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

A new optical tissue phantom is presented, which consists of a polymer film containing scatterers and absorbers. With this tissue phantom, tissue models can be constructed having optical properties and layered structures similar to those in living tissue. Optical properties can be specified for each layer, with a resolution of 20 micrometers. With this tissue phantom, a new laser Doppler testing principle is developed using a repetitive construction of static and moving layers. In this paper, the consequences of the usage of uniform motion in thin layers are discussed, as compared with the more random motion of blood in tissue. This issue is studied by means of Monte Carlo simulations. Measurements are shown performed with a laser Doppler imager. In particular, the normalization of the flux signal is discussed. It turns out, that normalization with the DC-level of the backscattered light gives better images than normalization with DC². Also, results of depth sensitivity measurements are shown.

Citation Download Citation

Wiendelt Steenbergen and Frits F. M. de Mul "Application of a novel laser Doppler tester including a sustainable tissue phantom", Proc. SPIE 3252, Optical Diagnostics of Biological Fluids III, (19 June 1998); https://doi.org/10.1117/12.311891

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