Paper
13 January 1998 Evaluation of early rheumatic disorders in PIP joints using a cw-transillumination method: first clinical results
Viravuth Prapavat, Till Luhmann, Andreas Krause, Marina Backhaus, Juergen Beuthan, Gerhard J. Mueller
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Abstract
This paper presents first clinical results of an in vivo experimental study on the detection of early pathological changes of rheumatoid arthritis (RA) using a near IR cw- transillumination method on finger joints (PIP). The inflammation of a joint system when caused by RA leads to changes in the synovial membrane and synovial. Measurements have shown that these rheumatic induced processes results in a variation in optical properties within the joint system. Using a cw system the PIP-joint is transilluminated with diode lasers at the articular cavity in order to use the entire scattered distribution of the transmitted radiation intensity for diagnostic purposes. The study includes results of in vivo measurements on 24 joints with known status and the evaluation of the feasibility of different distribution properties for detection of early RA.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Viravuth Prapavat, Till Luhmann, Andreas Krause, Marina Backhaus, Juergen Beuthan, and Gerhard J. Mueller "Evaluation of early rheumatic disorders in PIP joints using a cw-transillumination method: first clinical results", Proc. SPIE 3196, Optical and Imaging Techniques for Biomonitoring III, (13 January 1998); https://doi.org/10.1117/12.297919
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Cited by 2 scholarly publications.
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KEYWORDS
In vivo imaging

Continuous wave operation

Diagnostics

Inflammation

Optical properties

Semiconductor lasers

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