Imaging of laser-induced strain in biological tissue: pulsed holmium laser ablation of bovine cornea

Guy P. Delacretaz; Joseph T. Walsh Jr.; Didier Beghuin

doi:10.1117/12.297899

14 January 1998 Imaging of laser-induced strain in biological tissue: pulsed holmium laser ablation of bovine cornea

Guy P. Delacretaz, Joseph T. Walsh Jr., Didier Beghuin

Proceedings Volume 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III; (1998) https://doi.org/10.1117/12.297899
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

Laser ablation of tissue can be accompanied by deleterious training. A polaroscopic technique was used to image induced strain. In a bovine cornea model, we demonstrate that strain induced by a cavitation bubble occurs over an area larger than the bubble. Further, although the bubble lifetime is only about 400 microseconds and the cornea tissue is strained greatly by the expanding and collapsing bubble, there is substantial strain for several milliseconds after the bubble collapse. The results indicate the utility of polaroscopic imaging as well as the magnitude and spatial extent of mechanical events at times long after the initiating mechanical insult.

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Guy P. Delacretaz, Joseph T. Walsh Jr., and Didier Beghuin "Imaging of laser-induced strain in biological tissue: pulsed holmium laser ablation of bovine cornea", Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); https://doi.org/10.1117/12.297899

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KEYWORDS

Cornea

Tissues

Laser tissue interaction

Natural surfaces

Cavitation

Pulsed laser operation

Holmium

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