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In the past, absolute quantification of tissue chromophore concentrations has not been possible using near infrared spectroscopy (NIRS). On the contrary, the Critikon 2020 Cerebral Redox Monitor (Johnson and Johnson Medical Ltd) provides real time quantified value for oxyhemoglobin (Hb02), deoxyhemoglobin (HbH) and total hemoglobin (THb) concentrations. It achieves quantification by incorporating the following features : • a 2 detectors approach (to delete extracranial contribution) • an algorithm based on quantified absorption spectra • inclusion of an optical pathlenght and a wavelength dependent scattering factors
O. Piazza,M. A. Pennisi,F. Gallizzi,M. Pietrangeli, andF. Della Corte
"Critikon 2020: a clinical experience", Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); https://doi.org/10.1117/12.301094
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O. Piazza, M. A. Pennisi, F. Gallizzi, M. Pietrangeli, F. Della Corte, "Critikon 2020: a clinical experience," Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); https://doi.org/10.1117/12.301094