Complexity and performance of on-chip biochemical assays

Anne R. Kopf-Sill; Theo Nikiforov; Luc J. Bousse; Rob Nagle; J. Wallace Parce

doi:10.1117/12.269974

31 March 1997 Complexity and performance of on-chip biochemical assays

Anne R. Kopf-Sill, Theo Nikiforov, Luc J. Bousse, Rob Nagle, J. Wallace Parce

Proceedings Volume 2978, Micro- and Nanofabricated Electro-Optical Mechanical Systems for Biomedical and Environmental Applications; (1997) https://doi.org/10.1117/12.269974
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

The use of microchips for performing biochemical processes has the potential to reduce reagent use and thus assay costs, increase throughput, and automate complex processes. We are building a multifunctional platform that provides sensing and actuation functions for a variety of microchip- based biochemical and analytical processes. Here we describe recent experiments that include on-chip dilution, reagent mixing, reaction, separation, and detection for important classes of biochemical assays. Issues in chip design and control are discussed.

Citation Download Citation

Anne R. Kopf-Sill, Theo Nikiforov, Luc J. Bousse, Rob Nagle, and J. Wallace Parce "Complexity and performance of on-chip biochemical assays", Proc. SPIE 2978, Micro- and Nanofabricated Electro-Optical Mechanical Systems for Biomedical and Environmental Applications, (31 March 1997); https://doi.org/10.1117/12.269974

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