Morphological and histological changes on skin induced by 1540-nm laser radiation

Alexei V. Lukashev; Valery P. Solovyev; Boris I. Denker; Vadimir I. Kaz'min

doi:10.1117/12.275252

2 May 1997 Morphological and histological changes on skin induced by 1540-nm laser radiation

Alexei V. Lukashev, Valery P. Solovyev, Boris I. Denker, Vadimir I. Kaz'min

Proceedings Volume 2974, Laser and Noncoherent Ocular Effects: Epidemiology, Prevention, and Treatment; (1997) https://doi.org/10.1117/12.275252
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

The dose-response relationship for producing different grades of burns on skin produced by single Er-glass laser pulse were determined for energy densities within the range 0.5-35 J/cm² and pulse duration 100 ns and 2.5 ms. The persistent lesions on skin were subdivided into four morphologically different groups vs. radiant exposure of laser pulses. Histological investigation were made at 1- and 3-days post-exposure. Different methods of tissue preparation were tried to obtain better contrast of laser induced changes in skin tissue. At the 1-day post-exposure we observed on the histological samples coagulation of surface tissue, epidermis and dermis of skin depending on radiant exposure. 3-days histological samples revealed tearing of tissue detrit and active epitalization of damaged tissue.

Citation Download Citation

Alexei V. Lukashev, Valery P. Solovyev, Boris I. Denker, and Vadimir I. Kaz'min "Morphological and histological changes on skin induced by 1540-nm laser radiation", Proc. SPIE 2974, Laser and Noncoherent Ocular Effects: Epidemiology, Prevention, and Treatment, (2 May 1997); https://doi.org/10.1117/12.275252

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