Diffuse polarization spectroscopy on tissue phantoms and biological cell suspensions

Andreas H. Hielscher; Judith R. Mourant; Irving J. Bigio

doi:10.1117/12.260821

6 December 1996 Diffuse polarization spectroscopy on tissue phantoms and biological cell suspensions

Andreas H. Hielscher, Judith R. Mourant, Irving J. Bigio

Proceedings Volume 2926, Optical Biopsies and Microscopic Techniques; (1996) https://doi.org/10.1117/12.260821
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

We present experimental results that show the spatial variations of the diffuse-backscattered intensity, when linearly polarized light is incident on highly scattering media. Experiments on polystyrene-sphere suspensions demonstrate that the radial and azimuthal variations of the observed pattern depend on the concentration and size of the particles constituting the scattering medium. Measurements performed on rodent-cell suspensions show the potential of this method for biological-cell characterization, especially the distinction between normal and cancerous cells.

Citation Download Citation

Andreas H. Hielscher, Judith R. Mourant, and Irving J. Bigio "Diffuse polarization spectroscopy on tissue phantoms and biological cell suspensions", Proc. SPIE 2926, Optical Biopsies and Microscopic Techniques, (6 December 1996); https://doi.org/10.1117/12.260821

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