Restenosis after hot-tip laser-balloon angioplasty: histologic evaluation of the samples removed by Simpson atherectomy

Enrico Barbieri; Pietro Tanganelli; Giuseppe Taddei; Antonio Perbellini; Vito Attino; Gianni Destro; Piero Zardini

doi:10.1117/12.44024

1 May 1991 Restenosis after hot-tip laser-balloon angioplasty: histologic evaluation of the samples removed by Simpson atherectomy

Enrico Barbieri, Pietro Tanganelli, Giuseppe Taddei, Antonio Perbellini, Vito Attino, Gianni Destro, Piero Zardini

Author Affiliations +

Proceedings Volume 1425, Diagnostic and Therapeutic Cardiovascular Interventions; (1991) https://doi.org/10.1117/12.44024
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Laser balloon angioplasty has been used in recent years to treat peripheral artery disease. Despite a primary success the technique is plagued by a high restenosis rate. Directional atherectomy was performed in a small group of patients affected by primitive stenosis or restenosis after an invasive procedure. Light microscopy, immunohistochemistry, and transmission electron microscopy have identified the cellular component of intimal hyperplasia as smooth muscle cells in an active synthetic phenotype. The arterial healing process after invasive procedures seems to develop similarly independently of the device employed.

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Enrico Barbieri, Pietro Tanganelli, Giuseppe Taddei, Antonio Perbellini, Vito Attino, Gianni Destro, and Piero Zardini "Restenosis after hot-tip laser-balloon angioplasty: histologic evaluation of the samples removed by Simpson atherectomy", Proc. SPIE 1425, Diagnostic and Therapeutic Cardiovascular Interventions, (1 May 1991); https://doi.org/10.1117/12.44024

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