Geometric phase in PS-OCT for deep accurate analysis of transparent biological anisotropic tissues

Oleg Angelsky; Dmytro Ivanskyi

doi:10.1117/12.3021746

12 June 2024 Geometric phase in PS-OCT for deep accurate analysis of transparent biological anisotropic tissues

Oleg Angelsky, Dmytro Ivanskyi

Proceedings Volume 13187, Advances in 3OM: Opto-Mechatronics, Opto-Mechanics, and Optical Metrology (3OM 2023); 1318704 (2024) https://doi.org/10.1117/12.3021746
Event: Advances in 3OM: Opto-Mechatronics, Opto-Mechanics, and Optical Metrology, 2023, Timisoara, Romania

Abstract

Possibilities of geometric phase using in low-coherence polarization-sensitive tomography tasks for noninvasive diagnostics of surface (subsurface) layers of transparent biological media (samples and tissues) are considered. Determination of the object fields’ geometric phase in the modified Mach-Zehnder interferometer allows one to reproduce the geometric structure (optical axis/collagen orientation) of birefringent biological medium. Polarization-interference noninvasive approach of diagnostics the collagen orientation structure of thin nanosized surface tissue layers is proposed at the first time. It is shown, that taking into account the information about top (surface) layer structure can significantly improve the accuracy of deeper (subsurface) layers parameters estimation. The proposed solution is a unique feature that is not accessible in classical polarization-sensitive techniques of information recovery on tissue structure.

Citation Download Citation

Oleg Angelsky and Dmytro Ivanskyi "Geometric phase in PS-OCT for deep accurate analysis of transparent biological anisotropic tissues", Proc. SPIE 13187, Advances in 3OM: Opto-Mechatronics, Opto-Mechanics, and Optical Metrology (3OM 2023), 1318704 (12 June 2024); https://doi.org/10.1117/12.3021746

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