Analysis of characteristics and photoacoustic imaging performance of exogenous contrast agents

Jung-Sub Wi; Jiwoong Kim; Myeong Yun Kim; Seongwook Choi; Hae Jue Jung; Chulhong Kim; Hee-Kyung Na

doi:10.1117/12.3000864

12 March 2024 Analysis of characteristics and photoacoustic imaging performance of exogenous contrast agents

Jung-Sub Wi, Jiwoong Kim, Myeong Yun Kim, Seongwook Choi, Hae Jue Jung, Chulhong Kim, Hee-Kyung Na

Proceedings Volume 12842, Photons Plus Ultrasound: Imaging and Sensing 2024; 1284212 (2024) https://doi.org/10.1117/12.3000864
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Photoacoustic imaging offers high spatial resolution, imaging depth, and molecular information, emerging as a promising biomedical imaging modality. In particular, when using exogenous contrast, the advantages of photoacoustic imaging can be more effectively utilized in preclinical and clinical studies. We provide a novel approach to screen and identify efficient photoacoustic performance as contrast agents of the metals. To accomplish this, we introduce a novel figure of merit that quantifies the potential performance of contrast agents. As a result of the quantification, we discover that Ti nanodiscs outperform Pt nanodiscs in terms of photoacoustic ability, which shows a similar level to Au nanodiscs. We compare these results by performing a photoacoustic phantom imaging experiment. The photoacoustic performance of the three materials is compared by comparing the signal intensity of the materials measured on the photoacoustic image for various wavelengths. The imaging results further support our findings, demonstrating the superior performance of Ti nanodiscs as contrast agents.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Jung-Sub Wi, Jiwoong Kim, Myeong Yun Kim, Seongwook Choi, Hae Jue Jung, Chulhong Kim, and Hee-Kyung Na "Analysis of characteristics and photoacoustic imaging performance of exogenous contrast agents", Proc. SPIE 12842, Photons Plus Ultrasound: Imaging and Sensing 2024, 1284212 (12 March 2024); https://doi.org/10.1117/12.3000864

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available