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12 March 2024 A high-resolution hyperspectral imaging system for the retina
Minh Ha Tran, Michelle Bryarly, Kelden Pruitt, Ling Ma, Baowei Fei
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Proceedings Volume 12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis; 1283604 (2024) https://doi.org/10.1117/12.3001647
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
In this study, we developed an imaging system that can acquire and produce high-resolution hyperspectral images of the retina. Our system combines the view from a high-resolution RGB camera and a snapshot hyperspectral camera together. The method is fast and can be constructed into a compact imaging device. We tested our system by imaging a calibrated color chart, biological tissues ex vivo, and a phantom of the human retina. By using image pansharpening methods, we were able to produce a high-resolution hyperspectral image. The images from the hyperspectral camera alone have a spatial resolution of 0.2 mm/pixel, whereas the pansharpened images have a spatial resolution of 0.1 mm/pixel, a 2x increase in spatial resolution. Our method has the potential to capture images of the retina rapidly. Our method preserves both the spatial and spectral fidelity, as shown by comparing the original hyperspectral images with the pansharpened images. The high-resolution hyperspectral imaging device can have a variety of applications in retina examinations.
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(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.
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Minh Ha Tran, Michelle Bryarly, Kelden Pruitt, Ling Ma, and Baowei Fei "A high-resolution hyperspectral imaging system for the retina", Proc. SPIE 12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis, 1283604 (12 March 2024); https://doi.org/10.1117/12.3001647
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KEYWORDS
Hyperspectral imaging
Retina
Imaging systems
Cameras
Retinal scanning
Tunable filters
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