In vivo study of photodynamic effect induced by combination of IPL and HMME

Weijin Peng; Xingran Guo; Huiqi Zhan; Cheng Ke; Xin Wang; Zheng Huang

doi:10.1117/12.2687527

27 November 2023 In vivo study of photodynamic effect induced by combination of IPL and HMME

Weijin Peng, Xingran Guo, Huiqi Zhan, Cheng Ke, Xin Wang, Zheng Huang

Proceedings Volume 12770, Optics in Health Care and Biomedical Optics XIII; 127702Y (2023) https://doi.org/10.1117/12.2687527
Event: SPIE/COS Photonics Asia, 2023, Beijing, China

Conference Poster

Abstract

Intense pulsed light (IPL) is an incoherent high intensity pulsed light source and commonly used in dermatology and aesthetics. Early studies suggest that the combination of IPL and photosensitizer can induce cellular phototoxicity. Hemoporfin is a domestic photosensitizer approved for PDT treatment of Portwine stain birthmarks. This in vivo study evaluated the feasibility of using IPL as a light source for the excitation of Hemoporfin in mouse model. Results showed that IPL+Hemoporfin could cause more severe photodamage than IPL alone group, which suggests that it might be feasible to use IPL as PDT light source.

(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Weijin Peng, Xingran Guo, Huiqi Zhan, Cheng Ke, Xin Wang, and Zheng Huang "In vivo study of photodynamic effect induced by combination of IPL and HMME", Proc. SPIE 12770, Optics in Health Care and Biomedical Optics XIII, 127702Y (27 November 2023); https://doi.org/10.1117/12.2687527

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