Study on influencing factors of atherosclerotic plaque characteristics based on numerical simulation

Yunfei Zhou; Hongguang Yang; Bin Cheng; Cheng Wang

doi:10.1117/12.2674606

28 April 2023 Study on influencing factors of atherosclerotic plaque characteristics based on numerical simulation

Yunfei Zhou, Hongguang Yang, Bin Cheng, Cheng Wang

Proceedings Volume 12626, International Conference on Signal Processing, Computer Networks, and Communications (SPCNC 2022); 1262608 (2023) https://doi.org/10.1117/12.2674606
Event: International Conference on Signal Processing, Computer Networks, and Communications (SPCNC 2022), 2022, Zhuhai, China

Abstract

Atherosclerotic plaque can cause severe stenosis of the arterial lumen. Blood flowing through the narrowed artery may have different flow characteristics, and produce different forces on the plaque surface and arterial wall. The turbulence and force field in the lumen may have serious effects on vascular endothelial cells, smooth muscle cells and circulating blood cells. At the same time, different plaque characteristics will affect the flow field in the blood vessel, thus affecting the stress distribution on the vessel wall. This paper mainly focuses on the influencing factors of different plaque characteristics. The finite element models with different patch characteristics are established for numerical simulation. The effects of plaque size (degree of stenosis), plaque spacing and plaque relative rotation angle on the stress distribution of vascular wall were calculated.

Citation Download Citation

Yunfei Zhou, Hongguang Yang, Bin Cheng, and Cheng Wang "Study on influencing factors of atherosclerotic plaque characteristics based on numerical simulation", Proc. SPIE 12626, International Conference on Signal Processing, Computer Networks, and Communications (SPCNC 2022), 1262608 (28 April 2023); https://doi.org/10.1117/12.2674606

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