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17 March 2023 Subject specific head modeling based on computed tomography for high-density diffuse optical tomography
Monalisa Munsi, Arefeh Sherafati, Adam T. Eggebrecht, Abraham Z. Snyder, Broc Burke, Zachary E. Markow, Tracy M. Burns-Yocum, Heather M. Lugar, Anagha Narayanan, Tasha Doty, Sarah A. Eisenstein, Alexandra M. Svoboda, Mariel L. Schroeder, Mwiza Ushe, Tamara Hershey, Joseph P. Culver
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Proceedings Volume 12364, Clinical and Translational Neurophotonics 2023; 123640D (2023) https://doi.org/10.1117/12.2650250
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
High-density diffuse optical tomography (HD-DOT) has been shown to be a promising alternative to fMRI for mapping cortical hemodynamics in young healthy adults. HD-DOT imaging can be more precise when coupled with subject specific head models rather than generic atlas-based head models. While MRI-derived head models are commonly used, in some patient groups including subjects with metal and/or electrical implants, only CT images can be obtained. In this study, we developed a CT-based head modeling pipeline and demonstrated the feasibility of improved mapping of brain responses to tasks compared to a generic atlas-based head-model.
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Monalisa Munsi, Arefeh Sherafati, Adam T. Eggebrecht, Abraham Z. Snyder, Broc Burke, Zachary E. Markow, Tracy M. Burns-Yocum, Heather M. Lugar, Anagha Narayanan, Tasha Doty, Sarah A. Eisenstein, Alexandra M. Svoboda, Mariel L. Schroeder, Mwiza Ushe, Tamara Hershey, and Joseph P. Culver "Subject specific head modeling based on computed tomography for high-density diffuse optical tomography", Proc. SPIE 12364, Clinical and Translational Neurophotonics 2023, 123640D (17 March 2023); https://doi.org/10.1117/12.2650250
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KEYWORDS
Head
Computed tomography
Diffuse optical tomography
Image segmentation
Brain
Magnetic resonance imaging
Brain mapping
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