A theoretical model for the delivery of magnetic nanoparticles through a blood vessel under the influence of a magnetic field

S. F. Salem; V. V. Tuchin

doi:10.1117/12.2590823

4 May 2021 A theoretical model for the delivery of magnetic nanoparticles through a blood vessel under the influence of a magnetic field

S. F. Salem, V. V. Tuchin

Author Affiliations +

Proceedings Volume 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine; 1184519 (2021) https://doi.org/10.1117/12.2590823
Event: Saratov Fall Meeting 2020, 2020, Saratov, Russian Federation

Abstract

Magnetic nanoparticles, such as Superparamagnetic iron Oxide Nanoparticles (Fe₃O₄) are used in this theoretical study. These particles represent a unique nanoplatform with a great potential for the development of drug delivery systems via blood vessels, due to their biocompatibility and stability. The mechanisms of magnetic nanoparticles moving in Newtonian fluid (blood) in a static magnetic field are numerically studied. The equations of motion for particles in the flow are governed by a combination of magnetic equations for the permanent magnet field and the Navier-Stokes equations for fluid. These equations were solved numerically using the COMSOL Multiphysics Modeling Software.

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S. F. Salem and V. V. Tuchin "A theoretical model for the delivery of magnetic nanoparticles through a blood vessel under the influence of a magnetic field", Proc. SPIE 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine, 1184519 (4 May 2021); https://doi.org/10.1117/12.2590823

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