The premature brain embodies an underdeveloped vascular system, which can lead to poor cerebral blood flow (CBF), impaired metabolism, and subsequent brain injury. NNeMo (Neonatal NeuroMonitor) is an in-house built brain monitor that provides continuous and simultaneous measurements of CBF, tissue saturation (StO2), and metabolism. Nine premature infants were monitored for 6 h on day 1 and 3 of life. An oscillatory signal was observed in CBF and StO2 which diminished by day 3; metabolic response was not impacted by minor fluctuations in perfusion. Hemodynamic neuromonitoring could aid in predicting the onset of cerebral hemorrhaging or gauging brain injury severity.
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