Optical incoherence tomography: a method to generate tomographic retinal cross-sections with non-interferometric adaptive optics ophthalmoscopes

Serge Meimon; Elena Gofas-Salas; Michel Paques; Kate Grieve; Pedro Mecê

doi:10.1117/12.2576684

5 March 2021 Optical incoherence tomography: a method to generate tomographic retinal cross-sections with non-interferometric adaptive optics ophthalmoscopes

Serge Meimon, Elena Gofas-Salas, Michel Paques, Kate Grieve, Pedro Mecê

Author Affiliations +

Proceedings Volume 11623, Ophthalmic Technologies XXXI; 1162308 (2021) https://doi.org/10.1117/12.2576684
Event: SPIE BiOS, 2021, Online Only

Abstract

We present Optical Incoherence Tomography (OIT): a completely digital method to generate tomographic retinal cross-sections from en-face through-focus image stacks acquired by non-interferometric imaging systems, such as en-face adaptive optics (AO)-ophthalmoscopes. We show how to use OIT to guide focus position in cases where the user is “blind" focusing, such as auto fluorescence imaging of the Retinal Pigment Epithelium (RPE). We also demonstrate that OIT can produce distinctive cross-sectional views of the retina using back-scattered, multiply-scattered or even fluorescent light, making it a complementary technique to OCT.

Conference Presentation

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Serge Meimon, Elena Gofas-Salas, Michel Paques, Kate Grieve, and Pedro Mecê "Optical incoherence tomography: a method to generate tomographic retinal cross-sections with non-interferometric adaptive optics ophthalmoscopes", Proc. SPIE 11623, Ophthalmic Technologies XXXI, 1162308 (5 March 2021); https://doi.org/10.1117/12.2576684

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