Potentially high-throughput screening system for genetically encoded photoacoustic probe based on ring array detection

Xuanhao Wang; Mingshu Zhang; Lijuan Ma; Pingyong Xu; Cheng Ma

doi:10.1117/12.2574899

10 October 2020 Potentially high-throughput screening system for genetically encoded photoacoustic probe based on ring array detection

Xuanhao Wang, Mingshu Zhang, Lijuan Ma, Pingyong Xu, Cheng Ma

Author Affiliations +

Proceedings Volume 11553, Optics in Health Care and Biomedical Optics X; 115532F (2020) https://doi.org/10.1117/12.2574899
Event: SPIE/COS Photonics Asia, 2020, Online Only

Conference Poster

Abstract

Photoacoustic (PA) tomography (PACT) ’s capability is evidently influenced by the availability of imaging probes such as the genetically encoded proteins with near-infrared optical absorption (NIR-GEP). We present a new PACT screening platform specially designed for high throughput imaging and quantification of PA signal strengths from randomly mutated NIR-GEP candidates expressed in Escherichia coli colonies.The new platform holds promise to facilitate research on the next generation NIR PA imaging probes.

Conference Presentation

Citation Download Citation

Xuanhao Wang, Mingshu Zhang, Lijuan Ma, Pingyong Xu, and Cheng Ma "Potentially high-throughput screening system for genetically encoded photoacoustic probe based on ring array detection", Proc. SPIE 11553, Optics in Health Care and Biomedical Optics X, 115532F (10 October 2020); https://doi.org/10.1117/12.2574899

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