Photothermal therapy method based on photoacoustic/ultrasonic dual-mode temperature measurement and regulation

Yiming Ma; Liyong Ma; Cheng Ma; Yawei Qu; Yuanyuan Gao; Mingjian Sun

doi:10.1117/12.2573886

10 October 2020 Photothermal therapy method based on photoacoustic/ultrasonic dual-mode temperature measurement and regulation

Yiming Ma, Liyong Ma, Cheng Ma, Yawei Qu, Yuanyuan Gao, Mingjian Sun

Author Affiliations +

Proceedings Volume 11553, Optics in Health Care and Biomedical Optics X; 1155322 (2020) https://doi.org/10.1117/12.2573886
Event: SPIE/COS Photonics Asia, 2020, Online Only

Conference Poster

Abstract

Tumor photothermal therapy technology has received a lot of attention in recent years due to its non-invasive and targeted properties. However, how to ensure the safety and effectiveness of the photothermal treatment process poses new challenges to researchers. The field of photothermal therapy urgently needs a non-contact and accurate temperature detection method. In this paper, we have proposed a precise temperature detection technology based on photoacoustic and ultrasonic dual mode which can provide accurate and non-contact temperature measurement, and the temperature information of the light-induced ultrasound signals was fused and applied to temperature detection. To validate our method, temperatures of phantom was measured within the temperature range that simulates the heating process of photothermal therapy, and the calculated temperature measurement error was finally within 1 °C. In particular, it was also verified that the measurement accuracy of this method is 30% higher than that of single photoacoustic temperature detection. The results suggested that our method can be potentially used for temperature monitoring during photothermal therapy.

Conference Presentation

Citation Download Citation

Yiming Ma, Liyong Ma, Cheng Ma, Yawei Qu, Yuanyuan Gao, and Mingjian Sun "Photothermal therapy method based on photoacoustic/ultrasonic dual-mode temperature measurement and regulation", Proc. SPIE 11553, Optics in Health Care and Biomedical Optics X, 1155322 (10 October 2020); https://doi.org/10.1117/12.2573886

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