Versatile optothermal micro/nanorobots for cellular biology

Hongru Ding; Zhihan Chen; Yuebing Zheng

doi:10.1117/12.2567534

20 August 2020 Versatile optothermal micro/nanorobots for cellular biology

Hongru Ding, Zhihan Chen, Yuebing Zheng

Proceedings Volume 11463, Optical Trapping and Optical Micromanipulation XVII; 114630E (2020) https://doi.org/10.1117/12.2567534
Event: SPIE Nanoscience + Engineering, 2020, Online Only

Abstract

Through innovative management of light, heat and electric field in opto-thermoplasmonic fluidics, we have developed a micro/nanorobot platform for versatile manipulation of variable synthetic micro/nanoparticles and biological cells. Five manipulation modes have been achieved and can be switched on-demand. High-throughput self-navigation of micro/nanorobots has been realized with feedback control. The multimodal and nanoscale manipulation enables in situ single-cell characterizations to achieve high-resolution 3D cellular imaging and membrane protein profiling with simple and low-power optics. With the superior functionalities and user-friendliness, our micro/nanorobot technique will become a powerful tool in colloid science, life sciences, and nanotechnology.

Conference Presentation

Citation Download Citation

Hongru Ding, Zhihan Chen, and Yuebing Zheng "Versatile optothermal micro/nanorobots for cellular biology", Proc. SPIE 11463, Optical Trapping and Optical Micromanipulation XVII, 114630E (20 August 2020); https://doi.org/10.1117/12.2567534

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