Core/Shell Iron Oxide@Gold nanoparticles for dual-modal CT/MRI imaging

Oshra Betzer; Menachem Motiei; Tamar Dreifuss; Tamar Sadan; Noam Omer; Tamar Blumenfeld-Katzir; Zhuang Liu; Noam Ben-Eliezer; Rachela Popovtzer

doi:10.1117/12.2548430

21 February 2020 Core/Shell Iron Oxide@Gold nanoparticles for dual-modal CT/MRI imaging

Oshra Betzer, Menachem Motiei, Tamar Dreifuss, Tamar Sadan, Noam Omer, Tamar Blumenfeld-Katzir, Zhuang Liu, Noam Ben-Eliezer, Rachela Popovtzer

Author Affiliations +

Proceedings Volume 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII; 112541F (2020) https://doi.org/10.1117/12.2548430
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Multimodal imaging, integrating different imaging modalities, is emerging as a promising strategy for improving both preclinical and clinical imaging. Computed tomography (CT) and magnetic resonance imaging (MRI) are among the widely clinically-used imaging techniques. These imaging modalities are used for disease diagnosis and screening, each providing different and complementary information about the patient and the disease state. Nanoparticles are considered promising contrast agents for in vivo imaging applications, providing improved imaging and targeting capabilities compared to the commonly used contrast compounds. In this project, we present the development of a novel hybrid nanostructure, comprising of iron oxide core and gold shell nanoparticle for dual model CT and MRI imaging. The hybrid structures presented herein have potential to serve as a unique platform for precision imaging.

Citation Download Citation

Oshra Betzer, Menachem Motiei, Tamar Dreifuss, Tamar Sadan, Noam Omer, Tamar Blumenfeld-Katzir, Zhuang Liu, Noam Ben-Eliezer, and Rachela Popovtzer "Core/Shell Iron Oxide@Gold nanoparticles for dual-modal CT/MRI imaging", Proc. SPIE 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII, 112541F (21 February 2020); https://doi.org/10.1117/12.2548430

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