Mitchell A. Kirby,1 John J. Pitre Jr.,1 David S. Li,1 Tueng T. Shen M.D.,1 Ruikang K. Wang,1 Matthew O'Donnell,1 Ivan M. Pelivanovhttps://orcid.org/0000-0003-4991-14811
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In assuming an isotropic model for soft-tissue, dynamic OCE can produce order of magnitude errors in Young’s modulus estimates relative to static mechanical tests. Considering corneal fiber arrangement, we propose a simplified transverse isotropic (TI) model of the cornea, which depends on moduli λ and μ and the independent modulus G (which affects the propagation of vertically polarized surface waves, such as those measured in OCE). Early theoretical and experimental studies suggest that this TI model of the cornea may greatly improve quantitative estimates of corneal mechanics obtained using dynamic OCE.
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Mitchell A. Kirby, John J. Pitre Jr., David S. Li, Tueng T. Shen M.D., Ruikang K. Wang, Matthew O'Donnell, Ivan M. Pelivanov, "An anisotropic model for evaluation of corneal elasticity in dynamic OCE (Conference Presentation)," Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 112420T (17 March 2020); https://doi.org/10.1117/12.2544449