Presentation
6 March 2020 All-optical reflection-mode microscopic histology of unstained human tissues (Conference Presentation)
Author Affiliations +
Abstract
Surgery remains the primary method of care for multiple types of solid cancer. The goal of surgical oncology is to remove all tumorous tissue from the body. Frozen sectioning is commonly used during surgery to assess margin status. However, this method can be unreliable as the slides can be difficult to interpret. Using a recently reported imaging modality, Photoacoustic Remote Sensing (PARS), we present the first in human non-contact histology-like imaging in reflection mode. Cellular morphology alongside blood vessels are imaged in the human breast, gastrointestinal, and skin tissues. These images then compared with conventional hematoxylin and eosin-stained samples.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Saad Rasheed Abbasi, Martin Le, Serene Abu-Sardanah, Benjamin Ecclestone, Kevan Bell, Deepak Dinakaran, Gilbert Bigras, John R. Mackey, and Parsin H. Reza "All-optical reflection-mode microscopic histology of unstained human tissues (Conference Presentation)", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 1124009 (6 March 2020); https://doi.org/10.1117/12.2545260
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KEYWORDS
Tissues

Visualization

Photoacoustic spectroscopy

Blood vessels

Surgery

Cancer

Oncology

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