CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11220 > Article
Presentation
10 March 2020 Fluorescence dosimetry for indoor-daylight photodynamic therapy: clinical results using wide-field imaging and point-probe measurements (Conference Presentation)
Alberto J. Ruiz, Ethan P. M. LaRochelle, Brian Pogue
Author Affiliations +
Proceedings Volume 11220, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIX; 1122007 (2020) https://doi.org/10.1117/12.2546997
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
Clinical use of photodynamic therapy (PDT) is widespread for treatment of actinic keratosis (AKs) based upon ALA induced Protoporphyrin IX (PpIX). Dosimetry of the PpIX levels at the point-of-care can help guide critical decisions in PDT, since studies have shown that initial PpIX accumulation and PDT-induced photobleaching serve as strong indicators for patient outcomes in treatment. Here, we present clinical results using a point-probe spectral dosimeter alongside a translational wide-field cellphone fluorescence system to study outcomes of indoor-daylight PDT for treatment of AKs. The outcomes of this study help advance adoption of point-of-care dosimetry for PDT guidance and helps establish threshold treatment parameters for indoor-daylight PDT.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Alberto J. Ruiz, Ethan P. M. LaRochelle, and Brian Pogue "Fluorescence dosimetry for indoor-daylight photodynamic therapy: clinical results using wide-field imaging and point-probe measurements (Conference Presentation)", Proc. SPIE 11220, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIX, 1122007 (10 March 2020); https://doi.org/10.1117/12.2546997
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Photodynamic therapy
Luminescence
Point-of-care devices
Imaging systems
Skin cancer
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top