Achieving near-infrared deep tissue imaging via metal organic complex nanoparticles

Ye Wu; Jian Xu; Ruyan Guo

doi:10.1117/12.2534826

10 September 2019 Achieving near-infrared deep tissue imaging via metal organic complex nanoparticles

Ye Wu, Jian Xu, Ruyan Guo

Proceedings Volume 11123, Photonic Fiber and Crystal Devices: Advances in Materials and Innovations in Device Applications XIII; 111230Z (2019) https://doi.org/10.1117/12.2534826
Event: SPIE Optical Engineering + Applications, 2019, San Diego, California, United States

Abstract

The making of new nanomaterials for deep tissue imaging is important for clinic applications. In this work, Erbium based metal organic complex nanoparticles is synthesized. They show near-infrared fluorescence (800-1100 nm) when excited by 785 nm light. Deep tissues imaging is demonstrated using a nanoparticle-loaded 2 mL centrifuge tube covered with pig bacon meat tissue. The maximum imaging depth larger than 1.4 cm is achieved. Our work provides a validated procedure to make nanoparticles for near infrared deep tissue imaging.

Citation Download Citation

Ye Wu, Jian Xu, and Ruyan Guo "Achieving near-infrared deep tissue imaging via metal organic complex nanoparticles", Proc. SPIE 11123, Photonic Fiber and Crystal Devices: Advances in Materials and Innovations in Device Applications XIII, 111230Z (10 September 2019); https://doi.org/10.1117/12.2534826

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