DNA: Gold nanoparticles designed for mRNA sensing in cells: imaging of the gold nanoparticles using two photon photoluminescence spectroscopy.

Maria-Eleni Kyriazi; Otto L. Muskens; Antonios G. Kanaras

doi:10.1117/12.2502724

7 March 2019 DNA: Gold nanoparticles designed for mRNA sensing in cells: imaging of the gold nanoparticles using two photon photoluminescence spectroscopy.

Maria-Eleni Kyriazi, Otto L. Muskens, Antonios G. Kanaras

Author Affiliations +

Proceedings Volume 10892, Colloidal Nanoparticles for Biomedical Applications XIV; 108920C (2019) https://doi.org/10.1117/12.2502724
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Recently DNA-coated gold nanoparticles have emerged as ideal tools for the detection of mRNA in cells using dye modified oligonucleotides. However, the tracking of the gold core has been hindered by the small size of the particle core. In this work we utilize a home built set up and 43 nm DNA-coated spherical gold nanoparticles for the simultaneous imaging of mRNA detection using fluorescence microscopy and the gold nanoparticle core using two photon photoluminescence (TPPL).

Citation Download Citation

Maria-Eleni Kyriazi, Otto L. Muskens, and Antonios G. Kanaras "DNA: Gold nanoparticles designed for mRNA sensing in cells: imaging of the gold nanoparticles using two photon photoluminescence spectroscopy.", Proc. SPIE 10892, Colloidal Nanoparticles for Biomedical Applications XIV, 108920C (7 March 2019); https://doi.org/10.1117/12.2502724

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available