Probes Containing Gamma Radiation Detectors For In Vivo Tumor Detection And Imaging

N. E. Hartsough; H. B. Barber; J. M. Woolfenden; H. H. Barrett; T. S. Hickernell; D. P. Kwo

doi:10.1117/12.952174

8 August 1989 Probes Containing Gamma Radiation Detectors For In Vivo Tumor Detection And Imaging

N. E. Hartsough, H. B. Barber, J. M. Woolfenden, H. H. Barrett, T. S. Hickernell, D. P. Kwo

Proceedings Volume 1068, Catheter-Based Sensing and Imaging Technology; (1989) https://doi.org/10.1117/12.952174
Event: OE/LASE '89, 1989, Los Angeles, CA, United States

Abstract

External gamma-camera imaging using tumor-seeking radiotracers has been shown to be insensitive in the task of identifying small tumors situated deep inside the body. Our approach is to use probes containing miniature radiation detectors which, when maneuvered close to a tumor, overcome the limitations of external imaging. We discuss our results from using such probes for bronchoscopic and surgical tumor detection. A limitation that prevents the detection of small tumors with these probes is the spatial variation of the background count rate due to distant background sources of high radiotracer uptake. We present two techniques for solving this problem geometric background subtraction and imaging.

Citation Download Citation

N. E. Hartsough, H. B. Barber, J. M. Woolfenden, H. H. Barrett, T. S. Hickernell, and D. P. Kwo "Probes Containing Gamma Radiation Detectors For In Vivo Tumor Detection And Imaging", Proc. SPIE 1068, Catheter-Based Sensing and Imaging Technology, (8 August 1989); https://doi.org/10.1117/12.952174

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available