Handheld high resolution multispectral imaging device for study of Cushing syndrome (Conference Presentation)

Siddharth Khare; Ali Afshari; Afrouz Anderson; Constantine A. Stratakis; Amir H. Gandjbakhche

doi:10.1117/12.2306093

15 May 2018 Handheld high resolution multispectral imaging device for study of Cushing syndrome (Conference Presentation)

Siddharth Khare, Ali Afshari, Afrouz Anderson, Constantine A. Stratakis, Amir H. Gandjbakhche

Author Affiliations +

Proceedings Volume 10662, Smart Biomedical and Physiological Sensor Technology XV; 106620G (2018) https://doi.org/10.1117/12.2306093
Event: SPIE Commercial + Scientific Sensing and Imaging, 2018, Orlando, FL, United States

Abstract

Point-of-care technologies have become increasingly important in diagnostic applications. Wireless capabilities provide easy storage and analysis of data. Thus, portable systems need to migrate to handheld versions. Previously we have been able to determine blood volume fraction and water content in human skin using near-infrared (NIR) imaging. We have also used this portable multispectral imager to successfully identify remission of disease after treatment in patients with Cushing disease. Here we present a handheld high resolution multispectral imager. This tool is designed to be light weight and easy to use to promote its use in any clinical setup. The device consists of a custom fabricated CMOS imaging camera with on-chip NIR filters, a 25mm lens and wireless communication electronics. Illumination is provided by a broad band incandescent lamp. The use of novel technology of on-chip filters avoids the need for large size filtering systems such as filter wheels, making it a handheld device. Eight NIR filters with wavelengths in the range 700 nm to 980 nm provide flexibility of detecting multiple chromophores in the skin such as oxy and deoxy hemoglobin, melanin etc. as well as water. Images are acquired simultaneously with exposure time of 300 ms to 500 ms. Each filtered image is about 340X340 pixel making it possible to use our curvature correction algorithm for accurate determination of parameters. Also, images at this resolution can provide reliable information about spatial variations. This tool can ultimately be used to the study other skin abnormalities such as Kaposi Sarcoma.

Conference Presentation

Citation Download Citation

Siddharth Khare, Ali Afshari, Afrouz Anderson, Constantine A. Stratakis, and Amir H. Gandjbakhche "Handheld high resolution multispectral imaging device for study of Cushing syndrome (Conference Presentation)", Proc. SPIE 10662, Smart Biomedical and Physiological Sensor Technology XV, 106620G (15 May 2018); https://doi.org/10.1117/12.2306093

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Image resolution

Multispectral imaging

Optical filters

Imaging devices

Image filtering

Near infrared

Skin

Show All Keywords

Keywords/Phrases

Search In:

Publication Years