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X-ray phase-contrast imaging methods exploit variations in an object’s 3D refractive index distribution to form projection or volumetric images of weakly absorbing objects. Such techniques can resolve subtle tissue structures by employing coherent imaging principles, but retain the ability of traditional (incoherent) X-ray methods to image deep into tissue. In this talk, we describe recent advancements in image formation methods for benchtop applications of X-ray phase-contrast imaging and tomography and present applications of pre-clinical in vivo imaging.
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Mark A. Anastasio, Frank Brooks, Sergey Komarov, Yujia Chen, Weimin Zhou, "Development of computed phase-sensitive x-ray imaging technologies for pre-clinical science (Conference Presentation)," Proc. SPIE 10632, Anomaly Detection and Imaging with X-Rays (ADIX) III, 106320I (14 May 2018); https://doi.org/10.1117/12.2309429