Complex polarimetric and spectral techniques in diagnostics of blood plasma of patients with ovarian cancer as a preliminary stage molecular genetic screening

B. Grzegorzewski; O. P. Peresunko; S. B. Yermolenko

doi:10.1117/12.2303948

18 January 2018 Complex polarimetric and spectral techniques in diagnostics of blood plasma of patients with ovarian cancer as a preliminary stage molecular genetic screening

B. Grzegorzewski, O. P. Peresunko, S. B. Yermolenko

Author Affiliations +

Proceedings Volume 10612, Thirteenth International Conference on Correlation Optics; 106121L (2018) https://doi.org/10.1117/12.2303948
Event: Thirteenth International Conference on Correlation Optics, 2017, Chernivtsi, Ukraine

Abstract

This work is devoted to the substantiation and selection of patients with ovarian cancer (OC) for the purpose of conducting expensive molecular genetic studies on genotyping. As diagnostic methods have been used ultraviolet spectrometry samples of blood plasma in the liquid state, infrared spectroscopy middle range (2,5 - 25 microns) dry residue of plasma polarization and laser diagnostic technique of thin histological sections of biological tissues. Obtained results showed that the use of spectrophotometry in the range of 1000-3000 cm^-1 allowed to establish quantitative parameters of the plasma absorption rate of blood of patients in the third group in different ranges, which would allow in the future to conduct an express analysis of the patient's condition (procedure screening) for further molecular-genetic typing on BRCA I and II.

Citation Download Citation

B. Grzegorzewski, O. P. Peresunko, and S. B. Yermolenko "Complex polarimetric and spectral techniques in diagnostics of blood plasma of patients with ovarian cancer as a preliminary stage molecular genetic screening", Proc. SPIE 10612, Thirteenth International Conference on Correlation Optics, 106121L (18 January 2018); https://doi.org/10.1117/12.2303948

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