X-ray luminescence computed tomography imaging via multiple intensity weighted narrow beam irradiation

Bo Feng; Feng Gao; Huijuan Zhao; Limin Zhang; Jiao Li; Zhongxing Zhou

doi:10.1117/12.2288919

13 February 2018 X-ray luminescence computed tomography imaging via multiple intensity weighted narrow beam irradiation

Bo Feng, Feng Gao, Huijuan Zhao, Limin Zhang, Jiao Li, Zhongxing Zhou

Proceedings Volume 10487, Multimodal Biomedical Imaging XIII; 104870O (2018) https://doi.org/10.1117/12.2288919
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

The purpose of this work is to introduce and study a novel x-ray beam irradiation pattern for X-ray Luminescence Computed Tomography (XLCT), termed multiple intensity-weighted narrow-beam irradiation. The proposed XLCT imaging method is studied through simulations of x-ray and diffuse lights propagation. The emitted optical photons from X-ray excitable nanophosphors were collected by optical fiber bundles from the right-side surface of the phantom. The implementation of image reconstruction is based on the simulated measurements from 6 or 12 angular projections in terms of 3 or 5 x-ray beams scanning mode. The proposed XLCT imaging method is compared against the constant intensity weighted narrow-beam XLCT. From the reconstructed XLCT images, we found that the Dice similarity and quantitative ratio of targets have a certain degree of improvement. The results demonstrated that the proposed method can offer simultaneously high image quality and fast image acquisition.

Citation Download Citation

Bo Feng, Feng Gao, Huijuan Zhao, Limin Zhang, Jiao Li, and Zhongxing Zhou "X-ray luminescence computed tomography imaging via multiple intensity weighted narrow beam irradiation", Proc. SPIE 10487, Multimodal Biomedical Imaging XIII, 104870O (13 February 2018); https://doi.org/10.1117/12.2288919

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KEYWORDS

X-ray imaging

Luminescence

Photons

Image quality

Numerical simulations

Imaging systems

Computed tomography

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