Interventional fluorescence spectroscopy: preliminary results to detect tumor margins during glioma resection with two fluorescence spectra of PpIX

L. M. Alston; J. Guyotat; L. Mahieu-Williame; M. Hebert; P. Kantapareddy; D. Meyronet; D. Rousseau; B. Montcel

doi:10.1117/12.2286110

28 July 2017 Interventional fluorescence spectroscopy: preliminary results to detect tumor margins during glioma resection with two fluorescence spectra of PpIX

L. M. Alston, J. Guyotat, L. Mahieu-Williame, M. Hebert, P. Kantapareddy, D. Meyronet, D. Rousseau, B. Montcel

Author Affiliations +

Proceedings Volume 10411, Clinical and Preclinical Optical Diagnostics; 104110C (2017) https://doi.org/10.1117/12.2286110
Event: European Conferences on Biomedical Optics, 2017, Munich, Germany

Abstract

We show the feasibility of using an intraoperative spectroscopic device to identify tumors margins during glioma resection. The collected fluorescence spectra is fitted with two reference spectra of PpIX and the contribution of each spectrum enables to overcome the sensitivity of current techniques by seeing tumor margins and low grade gliomas.

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L. M. Alston, J. Guyotat, L. Mahieu-Williame, M. Hebert, P. Kantapareddy, D. Meyronet, D. Rousseau, and B. Montcel "Interventional fluorescence spectroscopy: preliminary results to detect tumor margins during glioma resection with two fluorescence spectra of PpIX ", Proc. SPIE 10411, Clinical and Preclinical Optical Diagnostics, 104110C (28 July 2017); https://doi.org/10.1117/12.2286110

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