Detection of prostate specific antigen using silicon photonic crystal nanocavity resonator

Amrita Kumar Sana; Yoshiteru Amemiya; Takeshi Ikeda; Akio Kuroda; Shin Yokoyama

doi:10.1117/12.2251604

27 January 2017 Detection of prostate specific antigen using silicon photonic crystal nanocavity resonator

Amrita Kumar Sana, Yoshiteru Amemiya, Takeshi Ikeda, Akio Kuroda, Shin Yokoyama

Proceedings Volume 10111, Quantum Sensing and Nano Electronics and Photonics XIV; 1011138 (2017) https://doi.org/10.1117/12.2251604
Event: SPIE OPTO, 2017, San Francisco, California, United States

Abstract

In this work, we investigated photonic crystal (PhC) based double nanocavity resonator biosensor. The sensor performance has confirmed by both sucrose and prostate specific antigen (PSA, a protein biomarker associated with prostate cancer). The device sensitivity and quality factor in sucrose solution are 1571 nm/RIU (Refractive Index Unit) and 2×10⁵ respectively. By using special antigen-antibody reaction, we successfully detected PSA concentration as low as 0.5 ng/mL.

Citation Download Citation

Amrita Kumar Sana, Yoshiteru Amemiya, Takeshi Ikeda, Akio Kuroda, and Shin Yokoyama "Detection of prostate specific antigen using silicon photonic crystal nanocavity resonator", Proc. SPIE 10111, Quantum Sensing and Nano Electronics and Photonics XIV, 1011138 (27 January 2017); https://doi.org/10.1117/12.2251604

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