Research of transmissive near infrared spectroscopy for non-invasive blood glucose measurement

Wenming Yang; Ningfang Liao; Yasheng Li; Liwei Shao; Dehuang Huang

doi:10.1117/12.2243987

31 October 2016 Research of transmissive near infrared spectroscopy for non-invasive blood glucose measurement

Wenming Yang, Ningfang Liao, Yasheng Li, Liwei Shao, Dehuang Huang

Proceedings Volume 10024, Optics in Health Care and Biomedical Optics VII; 100241P (2016) https://doi.org/10.1117/12.2243987
Event: SPIE/COS Photonics Asia, 2016, Beijing, China

Abstract

Near infrared (NIR) has prospectively applied in non-invasive blood glucose measurement due to glucose absorption among the 1.0-2.5m spectral bands. However, this significant technology is hard to be developed because of other blood components and low signal-to-noise ratio (SNR). In this work, we presented a non-invasive glucose measurement system using Fourier transform spectrometer which will work in fingertips or other human body tissues. A refrigerated InGaAs detector with high quantum efficiency performing well in the range of 1.0-1.7μm wavelength is used to acquire transmissive radiation. Preliminary experiment investigations were set up to test glucose levels of aqueous solutions with different concentrations. The analytical modeling of the interferogram data is based on arithmetic Fourier transform and supported by the curvilineal characterization. Experimental results show the variation of light intensity among different glucose concentrations and emphasize the obvious absorption of glucose in NIR wave-range. This study confirms the suitability that NIR can be developed in non-invasive glucose measurement.

Citation Download Citation

Wenming Yang, Ningfang Liao, Yasheng Li, Liwei Shao, and Dehuang Huang "Research of transmissive near infrared spectroscopy for non-invasive blood glucose measurement", Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100241P (31 October 2016); https://doi.org/10.1117/12.2243987

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